1DLS

3D Structure View

CAVITIES

STRUCTURE SETTINGS

LIGANDS

Chain 1DLS_A

Spin

Focus

Transparency

More Info

GENERAL

TITLE

METHOTREXATE-RESISTANT VARIANTS OF HUMAN DIHYDROFOLATE REDUCTASE WITH SUBSTITUTION OF LEUCINE 22: KINETICS, CRYSTALLOGRAPHY AND POTENTIAL AS SELECTABLE MARKERS

DATE LAST MODIFIED

24 Feb 2009

RELEASE

20 Apr 1995

OBSOLETE

CLASSIFICATION

OXIDO-REDUCTASE

EXPERIMENT TYPE

X-RAY DIFFRACTION

SPACE GROUP

H 3

RESOLUTION RANGE HIGH

RESOLUTION RANGE LOW

PUBMED ID

7890613

DOI

10.1074/JBC.270.10.5057

PDBe

LIGANDS

490791 , 931919

Chains

Structure Chain	Target Protein	Gene	Expression System	Organism	Synonims	Actions
	P00374	POTENTIAL	--	HUMAN	--	Mutations

NGL Viewer is used for the molecular visualization.

AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402