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GENERAL
TITLE
DOUBLE MUTANT (C59R+S108N) PLASMODIUM FALCIPARUM DIHYDROFOLATE REDUCTASE-THYMIDYLATE SYNTHASE (PFDHFR-TS) COMPLEXED WITH PYRIMETHAMINE, NADPH, AND DUMP
DATE LAST MODIFIED
10 Nov 2021
RELEASE
6 May 2003
OBSOLETE
CLASSIFICATION
OXIDOREDUCTASE, TRANSFERASE
EXPERIMENT TYPE
X-RAY DIFFRACTION
SPACE GROUP
P 21 21 21
RESOLUTION RANGE HIGH
2.3
RESOLUTION RANGE LOW
23.83
PUBMED ID
DOI
10.1038/NSB921
PDBe
1J3J
Chains
| Structure Chain | Target Protein | Gene | Expression System | Organism | Synonims | Actions |
|---|---|---|---|---|---|---|
| P13922 | -- | ESCHERICHIA COLI BL21(DE3) | MALARIA PARASITE P. FALCIPARUM | -- | Mutations | |
| P32245 | -- | ESCHERICHIA COLI BL21(DE3) | MALARIA PARASITE P. FALCIPARUM | -- | ||
| P54311 | -- | ESCHERICHIA COLI BL21(DE3) | MALARIA PARASITE P. FALCIPARUM | -- | ||
| P63092 | -- | ESCHERICHIA COLI BL21(DE3) | MALARIA PARASITE P. FALCIPARUM | -- |
NGL Viewer is used for the molecular visualization.
- AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
- AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402