1K74

3D Structure View

CAVITIES

STRUCTURE SETTINGS

LIGANDS

Bioassembly 1K74_1

Chain 1K74_A

Chain 1K74_B

Chain 1K74_D

Chain 1K74_E

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GENERAL

TITLE

THE 2.3 ANGSTROM RESOLUTION CRYSTAL STRUCTURE OF THE HETERODIMER OF THE HUMAN PPARGAMMA AND RXRALPHA LIGAND BINDING DOMAINS RESPECTIVELY BOUND WITH GW409544 AND 9-CIS RETINOIC ACID AND CO-ACTIVATOR PEPTIDES.

DATE LAST MODIFIED

26 Dec 2012

RELEASE

5 Dec 2001

OBSOLETE

CLASSIFICATION

TRANSCRIPTION

EXPERIMENT TYPE

X-RAY DIFFRACTION

SPACE GROUP

P 21 21 21

RESOLUTION RANGE HIGH

2.3

RESOLUTION RANGE LOW

PUBMED ID

11698662

DOI

10.1073/PNAS.241410198

PDBe

1K74

LIGANDS

761564 , 1323584

Chains

Target Protein	Gene	Expression System	Organism	Synonims
P28072	--	ESCHERICHIA COLI	HUMAN	RXRALPHA
P28072	--	--	--	--
O14818	--	ESCHERICHIA COLI	HUMAN	PPARGAMMA
O14818	--	--	--	--

NGL Viewer is used for the molecular visualization.

AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402