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GENERAL
TITLE
CRYSTAL STRUCTURE AT 1.9 ANGSTROEMS RESOLUTION OF THE HOMODIMER OF HUMAN RXR ALPHA LIGAND BINDING DOMAIN BOUND TO THE SYNTHETIC AGONIST COMPOUND BMS 649 AND A COACTIVATOR PEPTIDE
DATE LAST MODIFIED
4 Aug 2021
RELEASE
23 Oct 2002
OBSOLETE
CLASSIFICATION
TRANSCRIPTION
EXPERIMENT TYPE
X-RAY DIFFRACTION
SPACE GROUP
P 1
RESOLUTION RANGE HIGH
1.9
RESOLUTION RANGE LOW
30
PUBMED ID
DOI
10.1210/ME.16.5.987
PDBe
1MZN
LIGANDS
Chains
| Structure Chain | Target Protein | Gene | Expression System | Organism | Synonyms | Actions | ||
|---|---|---|---|---|---|---|---|---|
| P19793 | -- | ESCHERICHIA COLI BL21(DE3) | HUMAN | RETINOIC ACID RECEPTOR RXR-ALPHA | HUMAN | RETINOIC ACID RECEPTOR RXR-ALPHA | Mutations | |
| Q15596 | -- | -- | SYNTHETIC CONSTRUCT | GRIP1 | SYNTHETIC CONSTRUCT | GRIP1 | Mutations | |
| P19793 | -- | ESCHERICHIA COLI BL21(DE3) | HUMAN | RETINOIC ACID RECEPTOR RXR-ALPHA | HUMAN | RETINOIC ACID RECEPTOR RXR-ALPHA | Mutations | |
| Q15596 | -- | -- | SYNTHETIC CONSTRUCT | GRIP1 | SYNTHETIC CONSTRUCT | GRIP1 | Mutations | |
| P19793 | -- | ESCHERICHIA COLI BL21(DE3) | HUMAN | RETINOIC ACID RECEPTOR RXR-ALPHA | HUMAN | RETINOIC ACID RECEPTOR RXR-ALPHA | Mutations | |
| Q15596 | -- | -- | SYNTHETIC CONSTRUCT | GRIP1 | SYNTHETIC CONSTRUCT | GRIP1 | Mutations | |
| P19793 | -- | ESCHERICHIA COLI BL21(DE3) | HUMAN | RETINOIC ACID RECEPTOR RXR-ALPHA | HUMAN | RETINOIC ACID RECEPTOR RXR-ALPHA | Mutations | |
| Q15596 | -- | -- | SYNTHETIC CONSTRUCT | GRIP1 | SYNTHETIC CONSTRUCT | GRIP1 | Mutations |
NGL Viewer is used for the molecular visualization.
- AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
- AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402