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GENERAL
TITLE
POTENT, SELECTIVE INHIBITORS OF PROTEIN TYROSINE PHOSPHATASE 1B USING A SECOND PHOSPHOTYROSINE BINDING SITE, COMPLEXED WITH COMPOUND 19.
DATE LAST MODIFIED
11 Oct 2017
RELEASE
20 May 2003
OBSOLETE
CLASSIFICATION
HYDROLASE
EXPERIMENT TYPE
X-RAY DIFFRACTION
SPACE GROUP
P 31 2 1
RESOLUTION RANGE HIGH
0.31
RESOLUTION RANGE LOW
50
PUBMED ID
DOI
10.1016/S0960-894X(03)00302-0
PDBe
--
LIGANDS

Chains

Structure ChainTarget ProteinGeneExpression SystemOrganismSynonymsActions
P18031 PTPN1 OR PTP1B ESCHERICHIA COLI HUMAN PROTEIN-TYROSINE PHOSPHATASE 1B, PTP-1B HUMAN
PROTEIN-TYROSINE PHOSPHATASE 1B, PTP-1B
Mutations
NGL Viewer is used for the molecular visualization.
  • AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
  • AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402