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GENERAL
TITLE
DISSECTING AND DESIGNING INHIBITOR SELECTIVITY DETERMINANTS AT THE S1 SITE USING AN ARTIFICIAL ALA190 PROTEASE (ALA190 UPA)
DATE LAST MODIFIED
27 Oct 2021
RELEASE
21 Sept 2004
OBSOLETE
CLASSIFICATION
SERINE PROTEASE, HYDROLASE
EXPERIMENT TYPE
X-RAY DIFFRACTION
SPACE GROUP
P 1 21 1
RESOLUTION RANGE HIGH
1.78
RESOLUTION RANGE LOW
25.78
PUBMED ID
DOI
10.1016/J.JMB.2004.09.032
PDBe
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LIGANDS

Chains

Structure ChainTarget ProteinGeneExpression SystemOrganismSynonymsActions
P05981 HPN OR TMPRSS1 PICHIA PASTORIS HUMAN TRANSMEMBRANE PROTEASE, SERINE 1 HUMAN
TRANSMEMBRANE PROTEASE, SERINE 1
Mutations
P05981 HPN OR TMPRSS1 PICHIA PASTORIS HUMAN TRANSMEMBRANE PROTEASE, SERINE 1 HUMAN
TRANSMEMBRANE PROTEASE, SERINE 1
Mutations
NGL Viewer is used for the molecular visualization.
  • AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
  • AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402