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GENERAL
TITLE
CRYSTAL STRUCTURE OF HUMAN ATIC IN COMPLEX WITH FOLATE- BASED INHIBITOR, BW2315U89UC
DATE LAST MODIFIED
24 Feb 2009
RELEASE
27 Apr 2004
OBSOLETE
CLASSIFICATION
TRANSFERASE, HYDROLASE
EXPERIMENT TYPE
X-RAY DIFFRACTION
SPACE GROUP
P 1 21 1
RESOLUTION RANGE HIGH
2.6
RESOLUTION RANGE LOW
20
PUBMED ID
DOI
10.1074/JBC.M313691200
LIGANDS

Chains

Structure ChainTarget ProteinGeneExpression SystemOrganismSynonymsActions
P31939 ATIC ESCHERICHIA COLI HUMAN ATICPHOSPHORIBOSYLAMINOIMIDAZOLECARBOXAMIDE FORMYLTRANSFERASE(AICAR TRANSFORMYLASE) AND IMP CYCLOHYDROLASE(INOSINICASE) (IMP SYNTHETASE) HUMAN
ATICPHOSPHORIBOSYLAMINOIMIDAZOLECARBOXAMIDE FORMYL ...
Mutations
P31939 ATIC ESCHERICHIA COLI HUMAN ATICPHOSPHORIBOSYLAMINOIMIDAZOLECARBOXAMIDE FORMYLTRANSFERASE(AICAR TRANSFORMYLASE) AND IMP CYCLOHYDROLASE(INOSINICASE) (IMP SYNTHETASE) HUMAN
ATICPHOSPHORIBOSYLAMINOIMIDAZOLECARBOXAMIDE FORMYL ...
Mutations
P31939 ATIC ESCHERICHIA COLI HUMAN ATICPHOSPHORIBOSYLAMINOIMIDAZOLECARBOXAMIDE FORMYLTRANSFERASE(AICAR TRANSFORMYLASE) AND IMP CYCLOHYDROLASE(INOSINICASE) (IMP SYNTHETASE) HUMAN
ATICPHOSPHORIBOSYLAMINOIMIDAZOLECARBOXAMIDE FORMYL ...
Mutations
P31939 ATIC ESCHERICHIA COLI HUMAN ATICPHOSPHORIBOSYLAMINOIMIDAZOLECARBOXAMIDE FORMYLTRANSFERASE(AICAR TRANSFORMYLASE) AND IMP CYCLOHYDROLASE(INOSINICASE) (IMP SYNTHETASE) HUMAN
ATICPHOSPHORIBOSYLAMINOIMIDAZOLECARBOXAMIDE FORMYL ...
Mutations
NGL Viewer is used for the molecular visualization.
  • AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
  • AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402