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GENERAL
TITLE
CRYSTAL STRUCTURE OF THE COMPLEX OF CASPASE-3 WITH A PRYAZINONE INHIBITOR
DATE LAST MODIFIED
11 Oct 2017
RELEASE
11 May 2004
OBSOLETE
CLASSIFICATION
HYDROLASE
EXPERIMENT TYPE
X-RAY DIFFRACTION
SPACE GROUP
P 1 21 1
RESOLUTION RANGE HIGH
2.2
RESOLUTION RANGE LOW
19.9
PUBMED ID
DOI
10.1021/JM0305523
PDBe
1RHJ
LIGANDS
Chains
| Structure Chain | Target Protein | Gene | Expression System | Organism | Synonyms | Actions | ||
|---|---|---|---|---|---|---|---|---|
| P42574 | CASP3, CPP32 | ESCHERICHIA COLI BL21(DE3) | HUMAN | CYSTEINE PROTEASE CPP32, YAMA PROTEIN, CPP-32, APOPAIN,CASP-3, SREBP CLEAVAGE ACTIVITY 1, SCA-1 | HUMAN | CYSTEINE PROTEASE CPP32, YAMA PROTEIN, CPP-32, APO ... | Mutations | |
| P42574 | CASP3, CPP32 | ESCHERICHIA COLI BL21(DE3) | HUMAN | CYSTEINE PROTEASE CPP32, YAMA PROTEIN, CPP-32, APOPAIN,CASP-3, SREBP CLEAVAGE ACTIVITY 1, SCA-1 | HUMAN | CYSTEINE PROTEASE CPP32, YAMA PROTEIN, CPP-32, APO ... | Mutations | |
| P42574 | CASP3, CPP32 | ESCHERICHIA COLI BL21(DE3) | HUMAN | CYSTEINE PROTEASE CPP32, YAMA PROTEIN, CPP-32, APOPAIN,CASP-3, SREBP CLEAVAGE ACTIVITY 1, SCA-1 | HUMAN | CYSTEINE PROTEASE CPP32, YAMA PROTEIN, CPP-32, APO ... | Mutations | |
| P42574 | CASP3, CPP32 | ESCHERICHIA COLI BL21(DE3) | HUMAN | CYSTEINE PROTEASE CPP32, YAMA PROTEIN, CPP-32, APOPAIN,CASP-3, SREBP CLEAVAGE ACTIVITY 1, SCA-1 | HUMAN | CYSTEINE PROTEASE CPP32, YAMA PROTEIN, CPP-32, APO ... | Mutations |
NGL Viewer is used for the molecular visualization.
- AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
- AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402