1S78 logo

1S78

3D Structure View

Loading...

More Info

GENERAL
TITLE
INSIGHTS INTO ERBB SIGNALING FROM THE STRUCTURE OF THE ERBB2- PERTUZUMAB COMPLEX
DATE LAST MODIFIED
29 Jul 2020
RELEASE
27 Apr 2004
OBSOLETE
CLASSIFICATION
TRANSFERASE
EXPERIMENT TYPE
X-RAY DIFFRACTION
SPACE GROUP
P 43 21 2
RESOLUTION RANGE HIGH
3.25
RESOLUTION RANGE LOW
30
PUBMED ID
DOI
10.1016/S1535-6108(04)00083-2

Chains

Structure ChainTarget ProteinGeneExpression SystemOrganismSynonymsActions
P04626 ERBB2, HER2, NGL, NEU CRICETULUS GRISEUS HUMAN P185ERBB2, NEU PROTO-ONCOGENE, C-ERBB-2, TYROSINE KINASE-TYPE CELL SURFACE RECEPTOR HER2, MLN 19 HUMAN
P185ERBB2, NEU PROTO-ONCOGENE, C-ERBB-2, TYROSINE ...
Mutations
P04626 ERBB2, HER2, NGL, NEU CRICETULUS GRISEUS HUMAN P185ERBB2, NEU PROTO-ONCOGENE, C-ERBB-2, TYROSINE KINASE-TYPE CELL SURFACE RECEPTOR HER2, MLN 19 HUMAN
P185ERBB2, NEU PROTO-ONCOGENE, C-ERBB-2, TYROSINE ...
Mutations
-- ESCHERICHIA COLI HOUSE MOUSE -- HOUSE MOUSE --
-- ESCHERICHIA COLI HOUSE MOUSE -- HOUSE MOUSE --
-- ESCHERICHIA COLI HOUSE MOUSE -- HOUSE MOUSE --
-- ESCHERICHIA COLI HOUSE MOUSE -- HOUSE MOUSE --
NGL Viewer is used for the molecular visualization.
  • AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
  • AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402