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GENERAL
TITLE
CRYSTAL STRUCTURES OF RECOMBINANT RAT CATHEPSIN B AND A CATHEPSIN B- INHIBITOR COMPLEX: IMPLICATIONS FOR STRUCTURE-BASED INHIBITOR DESIGN
DATE LAST MODIFIED
13 Jul 2011
RELEASE
10 Mar 1996
OBSOLETE
CLASSIFICATION
HYDROLASE/HYDROLASE INHIBITOR
EXPERIMENT TYPE
X-RAY DIFFRACTION
SPACE GROUP
P 1 21 1
RESOLUTION RANGE HIGH
1.9
RESOLUTION RANGE LOW
14.3
PUBMED ID
DOI
10.1074/JBC.270.10.5527
PDBe
--
LIGANDS

Chains

Structure ChainTarget ProteinGeneExpression SystemOrganismSynonymsActions
P00787 CDNA, CTSB SACCHAROMYCES CEREVISIAE BROWN RAT,RAT,RATS CATHEPSIN B1, RSG-2, CATHEPSIN B LIGHT CHAIN, CATHEPSIN BHEAVY CHAIN BROWN RAT,RAT,RATS
CATHEPSIN B1, RSG-2, CATHEPSIN B LIGHT CHAIN, CATH ...
Mutations
P00787 CDNA, CTSB SACCHAROMYCES CEREVISIAE BROWN RAT,RAT,RATS CATHEPSIN B1, RSG-2, CATHEPSIN B LIGHT CHAIN, CATHEPSIN BHEAVY CHAIN BROWN RAT,RAT,RATS
CATHEPSIN B1, RSG-2, CATHEPSIN B LIGHT CHAIN, CATH ...
Mutations
NGL Viewer is used for the molecular visualization.
  • AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
  • AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402