2GPL

3D Structure View

CAVITIES

STRUCTURE SETTINGS

LIGANDS

Chain 2GPL_1

Chain 2GPL_2

Chain 2GPL_A

Chain 2GPL_B

Chain 2GPL_C

Chain 2GPL_D

Chain 2GPL_E

Chain 2GPL_F

Chain 2GPL_G

Chain 2GPL_H

Chain 2GPL_I

Chain 2GPL_J

Chain 2GPL_K

Chain 2GPL_L

Chain 2GPL_M

Chain 2GPL_N

Chain 2GPL_O

Chain 2GPL_P

Chain 2GPL_Q

Chain 2GPL_R

Chain 2GPL_S

Chain 2GPL_T

Chain 2GPL_U

Chain 2GPL_V

Chain 2GPL_W

Chain 2GPL_X

Chain 2GPL_Y

Chain 2GPL_Z

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GENERAL

TITLE

TMC-95 BASED BIPHENYL-ETHER MACROCYCLES: SPECIFIC PROTEASOME INHIBITORS

DATE LAST MODIFIED

24 Feb 2009

RELEASE

11 Jul 2006

OBSOLETE

CLASSIFICATION

HYDROLASE

EXPERIMENT TYPE

X-RAY DIFFRACTION

SPACE GROUP

P 1 21 1

RESOLUTION RANGE HIGH

2.8

RESOLUTION RANGE LOW

PUBMED ID

16793518

DOI

10.1016/J.CHEMBIOL.2006.04.005

PDBe

LIGANDS

2691832

Chains

Target Protein	Gene	Expression System	Organism	Synonims	Actions
P30657	PRE4	SACCHAROMYCES CEREVISIAE	BAKER'S YEAST	MACROPAIN SUBUNIT PRE4, PROTEINASE YSCE SUBUNITPRE ...	Mutations
P38624	PRE3	SACCHAROMYCES CEREVISIAE	BAKER'S YEAST	MACROPAIN SUBUNIT PRE3, PROTEINASE YSCE SUBUNITPRE ...	Mutations
P38684	PRS4, PRE8	SACCHAROMYCES CEREVISIAE	BAKER'S YEAST	MACROPAIN SUBUNIT Y7, PROTEINASE YSCE SUBUNIT 7,MU ...
P00829	PRS5, PRE9	SACCHAROMYCES CEREVISIAE	BAKER'S YEAST	MACROPAIN SUBUNIT Y13, PROTEINASE YSCE SUBUNIT 13, ...
P0A953	PRE6	SACCHAROMYCES CEREVISIAE	BAKER'S YEAST	MACROPAIN SUBUNIT PRE6, PROTEINASE YSCE SUBUNITPRE ...
P50502	PUP2, DOA5	SACCHAROMYCES CEREVISIAE	BAKER'S YEAST	MACROPAIN SUBUNIT PUP2, PROTEINASE YSCE SUBUNITPUP ...
Q9UKV8	PRE5	SACCHAROMYCES CEREVISIAE	BAKER'S YEAST	MACROPAIN SUBUNIT PRE5, PROTEINASE YSCE SUBUNITPRE ...
P02213	PRS1, PRC1, PRE10	SACCHAROMYCES CEREVISIAE	BAKER'S YEAST	MACROPAIN SUBUNIT C1, PROTEINASE YSCE SUBUNIT 1,MU ...
P0A953	PRS2, PRC2, SCL1	SACCHAROMYCES CEREVISIAE	BAKER'S YEAST	MACROPAIN SUBUNIT C7- ALPHA, PROTEINASE YSCESUBUNI ...
P25043	PUP1	SACCHAROMYCES CEREVISIAE	BAKER'S YEAST	MACROPAIN SUBUNIT PUP1, PROTEINASE YSCE SUBUNITPUP ...	Mutations

NGL Viewer is used for the molecular visualization.

AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402