2P4I logo

2P4I

3D Structure View

Loading...

More Info

GENERAL
TITLE
EVOLUTION OF A HIGHLY SELECTIVE AND POTENT 2-(PYRIDIN-2-YL)- 1,3,5-TRIAZINE TIE-2 KINASE INHIBITOR
DATE LAST MODIFIED
24 Feb 2009
RELEASE
20 Mar 2007
OBSOLETE
CLASSIFICATION
TRANSFERASE
EXPERIMENT TYPE
X-RAY DIFFRACTION
SPACE GROUP
P 21 21 21
RESOLUTION RANGE HIGH
2.5
RESOLUTION RANGE LOW
20
PUBMED ID
DOI
10.1021/JM061107L
PDBe
--
LIGANDS

Chains

Structure ChainTarget ProteinGeneExpression SystemOrganismSynonimsActions
Q02763 TEK, TIE2 TRICHOPLUSIA NI HUMAN
TYROSINE-PROTEIN KINASE RECEPTOR TIE-2, HTIE2,TYRO ...
Mutations
Q02763 TEK, TIE2 TRICHOPLUSIA NI HUMAN
TYROSINE-PROTEIN KINASE RECEPTOR TIE-2, HTIE2,TYRO ...
Mutations
NGL Viewer is used for the molecular visualization.
  • AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
  • AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402