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GENERAL
TITLE
REPLACE: A STRATEGY FOR ITERATIVE DESIGN OF CYCLIN BINDING GROOVE INHIBITORS
DATE LAST MODIFIED
9 Oct 2019
RELEASE
27 Mar 2007
OBSOLETE
CLASSIFICATION
TRANSFERASE/INHIBITOR
EXPERIMENT TYPE
X-RAY DIFFRACTION
SPACE GROUP
P 21 21 21
RESOLUTION RANGE HIGH
2.06
RESOLUTION RANGE LOW
91.29
PUBMED ID
DOI
10.1002/CBIC.200600189

Chains

Structure ChainTarget ProteinGeneExpression SystemOrganismSynonimsActions
P24941 -- SPODOPTERA FRUGIPERDA HUMAN
CYCLIN-DEPENDENT KINASE 2, P33 PROTEIN KINASE
Mutations
P20248 -- ESCHERICHIA COLI HUMAN
CYCLIN A
Mutations
P24941 -- SPODOPTERA FRUGIPERDA HUMAN
CYCLIN-DEPENDENT KINASE 2, P33 PROTEIN KINASE
Mutations
P20248 -- ESCHERICHIA COLI HUMAN
CYCLIN A
Mutations
-- -- SYNTHETIC CONSTRUCT --
-- -- SYNTHETIC CONSTRUCT --
NGL Viewer is used for the molecular visualization.
  • AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
  • AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402