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GENERAL
TITLE
CRYSTAL STRUCTURE OF HIV-1 REVERSE TRANSCRIPTASE (RT) IN COMPLEX WITH TMC278 (RILPIVIRINE), A NON-NUCLEOSIDE RT INHIBITOR
DATE LAST MODIFIED
10 Nov 2021
RELEASE
12 Feb 2008
OBSOLETE
CLASSIFICATION
TRANSFERASE, HYDROLASE/INHIBITOR
EXPERIMENT TYPE
X-RAY DIFFRACTION
SPACE GROUP
C 1 2 1
RESOLUTION RANGE HIGH
1.8
RESOLUTION RANGE LOW
50
PUBMED ID
DOI
10.1073/PNAS.0711209105

Chains

Structure ChainTarget ProteinGeneExpression SystemOrganismSynonymsActions
P03366 GAG-POL ESCHERICHIA COLI HUMAN IMMUNODEFICIENCY VIRUS 1 REVERSE TRANSCRIPTASE P66 SUBUNIT HUMAN IMMUNODEFICIENCY VIRUS 1
REVERSE TRANSCRIPTASE P66 SUBUNIT
Mutations
P03366 GAG-POL ESCHERICHIA COLI HUMAN IMMUNODEFICIENCY VIRUS 1 REVERSE TRANSCRIPTASE P51 SUBUNIT HUMAN IMMUNODEFICIENCY VIRUS 1
REVERSE TRANSCRIPTASE P51 SUBUNIT
Mutations
NGL Viewer is used for the molecular visualization.
  • AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
  • AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402