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GENERAL
TITLE
CRYSTAL STRUCTURE OF HUMAN MPS1 CATALYTIC DOMAIN T686A MUTANT IN COMPLEX WITH SP600125 INHIBITOR
DATE LAST MODIFIED
10 Nov 2021
RELEASE
13 May 2008
OBSOLETE
CLASSIFICATION
TRANSFERASE
EXPERIMENT TYPE
X-RAY DIFFRACTION
SPACE GROUP
I 2 2 2
RESOLUTION RANGE HIGH
2.88
RESOLUTION RANGE LOW
59.76
PUBMED ID
DOI
10.1074/JBC.M803026200
PDBe
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Chains

Structure ChainTarget ProteinGeneExpression SystemOrganismSynonymsActions
P33981 TTK, MPS1L1 ESCHERICHIA COLI HUMAN MONOPOLAR SPINDLE 1, PHOSPHOTYROSINE PICKED THREONINE-PROTEIN KINASE, PYT HUMAN
MONOPOLAR SPINDLE 1, PHOSPHOTYROSINE PICKED THREON ...
Mutations
NGL Viewer is used for the molecular visualization.
  • AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
  • AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402