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GENERAL
TITLE
CRYSTAL STRUCTURE OF PDE5A1 CATALYTIC DOMAIN IN COMPLEX WITH VARDENAFIL
DATE LAST MODIFIED
24 Feb 2009
RELEASE
20 May 2008
OBSOLETE
CLASSIFICATION
HYDROLASE
EXPERIMENT TYPE
X-RAY DIFFRACTION
SPACE GROUP
P 21 21 21
RESOLUTION RANGE HIGH
2.07
RESOLUTION RANGE LOW
30
PUBMED ID
DOI
10.1124/MOL.107.040212
LIGANDS

Chains

Structure ChainTarget ProteinGeneExpression SystemOrganismSynonymsActions
O76074 PDE5A, PDE5 ESCHERICHIA COLI HUMAN CGB-PDE, CGMP-BINDING CGMP-SPECIFICPHOSPHODIESTERASE HUMAN
CGB-PDE, CGMP-BINDING CGMP-SPECIFICPHOSPHODIESTERA ...
Mutations
O76074 PDE5A, PDE5 ESCHERICHIA COLI HUMAN CGB-PDE, CGMP-BINDING CGMP-SPECIFICPHOSPHODIESTERASE HUMAN
CGB-PDE, CGMP-BINDING CGMP-SPECIFICPHOSPHODIESTERA ...
Mutations
NGL Viewer is used for the molecular visualization.
  • AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
  • AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402