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GENERAL
TITLE
CRYSTAL STRUCTURE OF HUMAN PROSTACYCLIN SYNTHASE IN COMPLEX WITH INHIBITOR MINOXIDIL
DATE LAST MODIFIED
29 Jul 2020
RELEASE
20 Nov 2007
OBSOLETE
CLASSIFICATION
ISOMERASE
EXPERIMENT TYPE
X-RAY DIFFRACTION
SPACE GROUP
P 1 21 1
RESOLUTION RANGE HIGH
1.62
RESOLUTION RANGE LOW
30
PUBMED ID
DOI
10.1074/JBC.M707470200

Chains

Structure ChainTarget ProteinGeneExpression SystemOrganismSynonymsActions
Q16647 PTGIS, CYP8, CYP8A1 ESCHERICHIA COLI BL21(DE3) HUMAN CYTOCHROME P450 8A1, PROSTAGLANDIN I2 SYNTHASE HUMAN
CYTOCHROME P450 8A1, PROSTAGLANDIN I2 SYNTHASE
Mutations
Q16647 PTGIS, CYP8, CYP8A1 ESCHERICHIA COLI BL21(DE3) HUMAN CYTOCHROME P450 8A1, PROSTAGLANDIN I2 SYNTHASE HUMAN
CYTOCHROME P450 8A1, PROSTAGLANDIN I2 SYNTHASE
Mutations
NGL Viewer is used for the molecular visualization.
  • AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
  • AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402