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GENERAL
TITLE
CRYSTAL STRUCTURE OF THE TYROSINE KINASE DOMAIN OF THE HEPATOCYTE GROWTH FACTOR RECEPTOR C-MET IN COMPLEX WITH A PYRROLOTRIAZINE BASED INHIBITOR
DATE LAST MODIFIED
20 Oct 2021
RELEASE
18 Mar 2008
OBSOLETE
CLASSIFICATION
TRANSFERASE
EXPERIMENT TYPE
X-RAY DIFFRACTION
SPACE GROUP
P 21 21 21
RESOLUTION RANGE HIGH
2.17
RESOLUTION RANGE LOW
50
PUBMED ID
DOI
10.1016/J.BMCL.2008.01.121
LIGANDS

Chains

Structure ChainTarget ProteinGeneExpression SystemOrganismSynonymsActions
P08581 MET SPODOPTERA FRUGIPERDA HUMAN MET PROTO-ONCOGENE TYROSINE KINASE, C-MET, HGF RECEPTOR,HGF/SF RECEPTOR, SF RECEPTOR, SCATTER FACTOR RECEPTOR HUMAN
MET PROTO-ONCOGENE TYROSINE KINASE, C-MET, HGF REC ...
Mutations
NGL Viewer is used for the molecular visualization.
  • AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
  • AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402