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GENERAL
TITLE
CRYSTAL STRUCTURE OF AURORA A IN COMPLEX WITH VX-680 AND TPX2
DATE LAST MODIFIED
13 Jul 2011
RELEASE
28 Oct 2008
OBSOLETE
CLASSIFICATION
TRANSFERASE
EXPERIMENT TYPE
X-RAY DIFFRACTION
SPACE GROUP
C 2 2 21
RESOLUTION RANGE HIGH
2.3
RESOLUTION RANGE LOW
50
PUBMED ID
DOI
10.1110/PS.036590.108

Chains

Structure ChainTarget ProteinGeneExpression SystemOrganismSynonymsActions
O14965 AURKA, AIK, ARK1, AURA, BTAK, STK15, STK6 ESCHERICHIA COLI HOMO SAPIENS AURORA KINASE A, AURORA-A, SERINE/THREONINE KINASE 15,AURORA/IPL1-RELATED KINASE 1, AURORA-RELATED KINASE 1, HARK1, BREASTTUMOR-AMPLIFIED KINASE HOMO SAPIENS
AURORA KINASE A, AURORA-A, SERINE/THREONINE KINASE ...
Mutations
Q9ULW0 TPX2, C20ORF1, C20ORF2, DIL2, HCA519 ESCHERICHIA COLI HOMO SAPIENS TPX2, RESTRICTED EXPRESSION PROLIFERATION-ASSOCIATED PROTEIN100, P100, DIFFERENTIALLY EXPRESSED IN CANCEROUS AND NON-CANCEROUSLUNG CELLS 2, DIL-2, PROTEIN FLS353, HEPATOCELLULAR CARCINOMA-ASSOCIATED ANTIGEN 519 HOMO SAPIENS
TPX2, RESTRICTED EXPRESSION PROLIFERATION-ASSOCIAT ...
Mutations
NGL Viewer is used for the molecular visualization.
  • AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
  • AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402