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GENERAL
TITLE
X-RAY STRUCTURE OF THE HUMAN MITOGEN-ACTIVATED PROTEIN KINASE KINASE 1 (MEK1) COMPLEXED WITH A POTENT INHIBITOR RDEA119 AND MGATP
DATE LAST MODIFIED
15 Sept 2009
RELEASE
1 Sept 2009
OBSOLETE
CLASSIFICATION
TRANSFERASE
EXPERIMENT TYPE
X-RAY DIFFRACTION
SPACE GROUP
P 62
RESOLUTION RANGE HIGH
2.5
RESOLUTION RANGE LOW
99
PUBMED ID
DOI
10.1158/0008-5472.CAN-09-0679
PDBe
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Chains

Structure ChainTarget ProteinGeneExpression SystemOrganismSynonymsActions
Q02750 MEK1 ESCHERICHIA COLI HOMO SAPIENS MAP KINASE KINASE 1, MAPKK 1, ERK ACTIVATOR KINASE1, MAPK/ERK KINASE 1, MEK1 HOMO SAPIENS
MAP KINASE KINASE 1, MAPKK 1, ERK ACTIVATOR KINASE ...
Mutations
NGL Viewer is used for the molecular visualization.
  • AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
  • AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402