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GENERAL
TITLE
CDK2/CYCLINA COMPLEXED WITH A PYRAZOLOPYRIDAZINE INHIBITOR
DATE LAST MODIFIED
24 Jul 2019
RELEASE
21 Oct 2008
OBSOLETE
CLASSIFICATION
TRANSFERASE/CELL CYCLE
EXPERIMENT TYPE
X-RAY DIFFRACTION
SPACE GROUP
P 62 2 2
RESOLUTION RANGE HIGH
3.22
RESOLUTION RANGE LOW
160.13
PUBMED ID
DOI
10.1016/J.BMCL.2008.09.069
LIGANDS

Chains

Structure ChainTarget ProteinGeneExpression SystemOrganismSynonymsActions
P24941 CDK2 SPODOPTERA FRUGIPERDA HUMAN P33 PROTEIN KINASE HUMAN
P33 PROTEIN KINASE
Mutations
P20248 CCNA2, CCN1, CCNA ESCHERICHIA COLI HUMAN CYCLIN-A HUMAN
CYCLIN-A
Mutations
P24941 CDK2 SPODOPTERA FRUGIPERDA HUMAN P33 PROTEIN KINASE HUMAN
P33 PROTEIN KINASE
Mutations
P20248 CCNA2, CCN1, CCNA ESCHERICHIA COLI HUMAN CYCLIN-A HUMAN
CYCLIN-A
Mutations
NGL Viewer is used for the molecular visualization.
  • AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
  • AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402