3F82 logo

3F82

3D Structure View

Loading...

More Info

GENERAL
TITLE
CRYSTAL STRUCTURE OF THE TYROSINE KINASE DOMAIN OF THE HEPATOCYTE GROWTH FACTOR RECEPTOR C-MET IN COMPLEX WITH N-(4-(2-AMINO-3- CHLOROPYRIDIN-4-YLOXY)-3-FLUOROPHENYL)-4-ETHOXY-1-(4-FLUOROPHENYL)-2- OXO-1,2-DIHYDROPYRIDINE-3-CARBOXAMIDE
DATE LAST MODIFIED
20 Oct 2021
RELEASE
31 Mar 2009
OBSOLETE
CLASSIFICATION
TRANSFERASE
EXPERIMENT TYPE
X-RAY DIFFRACTION
SPACE GROUP
P 21 21 21
RESOLUTION RANGE HIGH
2.5
RESOLUTION RANGE LOW
25
PUBMED ID
DOI
10.1021/JM801586S
LIGANDS

Chains

Structure ChainTarget ProteinGeneExpression SystemOrganismSynonymsActions
P08581 MET SPODOPTERA FRUGIPERDA HUMAN HGF RECEPTOR, SCATTER FACTOR RECEPTOR, SF RECEPTOR, HGF/SFRECEPTOR, MET PROTO-ONCOGENE TYROSINE KINASE, C-MET HUMAN
HGF RECEPTOR, SCATTER FACTOR RECEPTOR, SF RECEPTOR ...
Mutations
NGL Viewer is used for the molecular visualization.
  • AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
  • AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402