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GENERAL
TITLE
P38 KINASE CRYSTAL STRUCTURE IN COMPLEX WITH 6-(2,4-DIFLUORO-PHENOXY)- 2-((R)-2-METHANESULFONYL-1-METHYL-ETHYLAMINO)-8-METHYL-8H-PYRIDO[2,3- D]PYRIMIDIN-7-ONE
DATE LAST MODIFIED
24 Jul 2019
RELEASE
22 Dec 2009
OBSOLETE
CLASSIFICATION
SIGNALING PROTEIN, TRANSFERASE
EXPERIMENT TYPE
X-RAY DIFFRACTION
SPACE GROUP
P 21 21 21
RESOLUTION RANGE HIGH
2.3
RESOLUTION RANGE LOW
50
PUBMED ID
-
DOI
--
LIGANDS

Chains

Structure ChainTarget ProteinGeneExpression SystemOrganismSynonymsActions
Q16539 CSBP, CSBP1, CSBP2, CSPB1, MAPK14, MXI2 ESCHERICHIA COLI HUMAN MITOGEN-ACTIVATED PROTEIN KINASE P38 ALPHA, MAP KINASE P38ALPHA, CYTOKINE SUPPRESSIVE ANTI-INFLAMMATORY DRUG-BINDING PROTEIN,CSAID-BINDING PROTEIN, CSBP, MAX-INTERACTING PROTEIN 2, MAP KINASEMXI2, SAPK2A HUMAN
MITOGEN-ACTIVATED PROTEIN KINASE P38 ALPHA, MAP KI ...
Mutations
NGL Viewer is used for the molecular visualization.
  • AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
  • AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402