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GENERAL
TITLE
CRYSTAL STRUCTURE OF ACTIVATED RECEPTOR TYROSINE KINASE IN COMPLEX WITH SUBSTRATES
DATE LAST MODIFIED
20 Oct 2021
RELEASE
18 Aug 2009
OBSOLETE
CLASSIFICATION
TRANSFERASE/TRANSFERASE INHIBITOR
EXPERIMENT TYPE
X-RAY DIFFRACTION
SPACE GROUP
C 1 2 1
RESOLUTION RANGE HIGH
2.5
RESOLUTION RANGE LOW
50
PUBMED ID
DOI
10.1016/J.CELL.2009.05.028
LIGANDS

Chains

Structure ChainTarget ProteinGeneExpression SystemOrganismSynonymsActions
P11362 FGFBR, FGFR1, FLG, FLT2 ESCHERICHIA COLI HUMAN FGFR-1, BFGF-R, FMS-LIKE TYROSINE KINASE 2, C-FGR HUMAN
FGFR-1, BFGF-R, FMS-LIKE TYROSINE KINASE 2, C-FGR
Mutations
P10686 PLCG1 ESCHERICHIA COLI RAT 1-PHOSPHATIDYLINOSITOL-4,5-BISPHOSPHATE PHOSPHODIESTERASEGAMMA-1, PHOSPHOINOSITIDE PHOSPHOLIPASE C, PLC-GAMMA-1, PLC-II, PLC-148 RAT
1-PHOSPHATIDYLINOSITOL-4,5-BISPHOSPHATE PHOSPHODIE ...
Mutations
NGL Viewer is used for the molecular visualization.
  • AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
  • AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402