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GENERAL
TITLE
STRUCTURES OF DIHYDROFOLATE REDUCTASE-THYMIDYLATE SYNTHASE OF TRYPANOSOMA CRUZI IN THE FOLATE-FREE STATE AND IN COMPLEX WITH TWO ANTIFOLATE DRUGS, TRIMETREXATE AND METHOTREXATE
DATE LAST MODIFIED
13 Jul 2011
RELEASE
19 May 2009
OBSOLETE
CLASSIFICATION
OXIDOREDUCTASE, TRANSFERASE
EXPERIMENT TYPE
X-RAY DIFFRACTION
SPACE GROUP
P 43 21 2
RESOLUTION RANGE HIGH
3
RESOLUTION RANGE LOW
24.97
PUBMED ID
DOI
10.1107/S090744490901230X

Chains

Structure ChainTarget ProteinGeneExpression SystemOrganismSynonimsActions
Q27793 DHFR-TS ESCHERICHIA COLI TRYPANOSOMA CRUZI -- Mutations
Q27793 DHFR-TS ESCHERICHIA COLI TRYPANOSOMA CRUZI -- Mutations
Q27793 DHFR-TS ESCHERICHIA COLI TRYPANOSOMA CRUZI -- Mutations
Q27793 DHFR-TS ESCHERICHIA COLI TRYPANOSOMA CRUZI -- Mutations
NGL Viewer is used for the molecular visualization.
  • AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
  • AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402