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GENERAL
TITLE
CRYSTAL STRUCTURE OF INSULIN-LIKE GROWTH FACTOR 1 RECEPTOR (IGF-1R-WT) COMPLEX WITH BMS-754807 [1-(4-((5-CYCLOPROPYL-1H-PYRAZOL-3-YL)AMINO) PYRROLO[2,1-F][1,2,4]TRIAZIN-2-YL)-N-(6-FLUORO-3-PYRIDINYL)-2-METHYL- L-PROLINAMIDE]
DATE LAST MODIFIED
1 Nov 2017
RELEASE
22 Dec 2009
OBSOLETE
CLASSIFICATION
HORMONE
EXPERIMENT TYPE
X-RAY DIFFRACTION
SPACE GROUP
C 1 2 1
RESOLUTION RANGE HIGH
2.08
RESOLUTION RANGE LOW
50
PUBMED ID
DOI
10.1021/JM900786R
PDBe
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LIGANDS

Chains

Structure ChainTarget ProteinGeneExpression SystemOrganismSynonymsActions
P08069 IGF1R SPODOPTERA FRUGIPERDA HUMAN INSULIN-LIKE GROWTH FACTOR I RECEPTOR, IGF-I RECEPTOR HUMAN
INSULIN-LIKE GROWTH FACTOR I RECEPTOR, IGF-I RECEP ...
Mutations
NGL Viewer is used for the molecular visualization.
  • AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
  • AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402