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GENERAL
TITLE
2-AMINOPYRAZOLO[1,5-A]PYRIMIDINES AS POTENT AND SELECTIVE INHIBITORS OF JAK2
DATE LAST MODIFIED
1 Nov 2017
RELEASE
10 Nov 2009
OBSOLETE
CLASSIFICATION
TRANSFERASE
EXPERIMENT TYPE
X-RAY DIFFRACTION
SPACE GROUP
C 2 2 21
RESOLUTION RANGE HIGH
2.6
RESOLUTION RANGE LOW
100
PUBMED ID
DOI
10.1016/J.BMCL.2009.10.053

Chains

Structure ChainTarget ProteinGeneExpression SystemOrganismSynonymsActions
O60674 JAK2 BACULOVIRUS HUMAN JANUS KINASE 2, JAK-2 HUMAN
JANUS KINASE 2, JAK-2
Mutations
NGL Viewer is used for the molecular visualization.
  • AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
  • AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402