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GENERAL
TITLE
MK2 COMPLEXED TO INHIBITOR N4-(7-(BENZOFURAN-2-YL)-1H-INDAZOL-5-YL) PYRIMIDINE-2,4-DIAMINE
DATE LAST MODIFIED
13 Jul 2011
RELEASE
12 Jan 2010
OBSOLETE
CLASSIFICATION
TRANSFERASE
EXPERIMENT TYPE
X-RAY DIFFRACTION
SPACE GROUP
P 21 21 21
RESOLUTION RANGE HIGH
2.9
RESOLUTION RANGE LOW
50
PUBMED ID
DOI
10.1016/J.BMCL.2009.10.102
LIGANDS

Chains

Structure ChainTarget ProteinGeneExpression SystemOrganismSynonymsActions
P49137 MAPKAPK2 ESCHERICHIA COLI HUMAN MAPK-ACTIVATED PROTEIN KINASE 2, MAPKAP KINASE 2, MAPKAPK-2,MK2 HUMAN
MAPK-ACTIVATED PROTEIN KINASE 2, MAPKAP KINASE 2, ...
Mutations
P49137 MAPKAPK2 ESCHERICHIA COLI HUMAN MAPK-ACTIVATED PROTEIN KINASE 2, MAPKAP KINASE 2, MAPKAPK-2,MK2 HUMAN
MAPK-ACTIVATED PROTEIN KINASE 2, MAPKAP KINASE 2, ...
Mutations
P49137 MAPKAPK2 ESCHERICHIA COLI HUMAN MAPK-ACTIVATED PROTEIN KINASE 2, MAPKAP KINASE 2, MAPKAPK-2,MK2 HUMAN
MAPK-ACTIVATED PROTEIN KINASE 2, MAPKAP KINASE 2, ...
Mutations
P49137 MAPKAPK2 ESCHERICHIA COLI HUMAN MAPK-ACTIVATED PROTEIN KINASE 2, MAPKAP KINASE 2, MAPKAPK-2,MK2 HUMAN
MAPK-ACTIVATED PROTEIN KINASE 2, MAPKAP KINASE 2, ...
Mutations
P49137 MAPKAPK2 ESCHERICHIA COLI HUMAN MAPK-ACTIVATED PROTEIN KINASE 2, MAPKAP KINASE 2, MAPKAPK-2,MK2 HUMAN
MAPK-ACTIVATED PROTEIN KINASE 2, MAPKAP KINASE 2, ...
Mutations
P49137 MAPKAPK2 ESCHERICHIA COLI HUMAN MAPK-ACTIVATED PROTEIN KINASE 2, MAPKAP KINASE 2, MAPKAPK-2,MK2 HUMAN
MAPK-ACTIVATED PROTEIN KINASE 2, MAPKAP KINASE 2, ...
Mutations
P49137 MAPKAPK2 ESCHERICHIA COLI HUMAN MAPK-ACTIVATED PROTEIN KINASE 2, MAPKAP KINASE 2, MAPKAPK-2,MK2 HUMAN
MAPK-ACTIVATED PROTEIN KINASE 2, MAPKAP KINASE 2, ...
Mutations
P49137 MAPKAPK2 ESCHERICHIA COLI HUMAN MAPK-ACTIVATED PROTEIN KINASE 2, MAPKAP KINASE 2, MAPKAPK-2,MK2 HUMAN
MAPK-ACTIVATED PROTEIN KINASE 2, MAPKAP KINASE 2, ...
Mutations
P49137 MAPKAPK2 ESCHERICHIA COLI HUMAN MAPK-ACTIVATED PROTEIN KINASE 2, MAPKAP KINASE 2, MAPKAPK-2,MK2 HUMAN
MAPK-ACTIVATED PROTEIN KINASE 2, MAPKAP KINASE 2, ...
Mutations
P49137 MAPKAPK2 ESCHERICHIA COLI HUMAN MAPK-ACTIVATED PROTEIN KINASE 2, MAPKAP KINASE 2, MAPKAPK-2,MK2 HUMAN
MAPK-ACTIVATED PROTEIN KINASE 2, MAPKAP KINASE 2, ...
Mutations
NGL Viewer is used for the molecular visualization.
  • AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
  • AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402