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GENERAL
TITLE
CRYSTAL STRUCTURE OF TGFBRI COMPLEXED WITH A PYRAZOLONE INHIBITOR
DATE LAST MODIFIED
23 Feb 2010
RELEASE
22 Dec 2009
OBSOLETE
CLASSIFICATION
TRANSFERASE
EXPERIMENT TYPE
X-RAY DIFFRACTION
SPACE GROUP
C 2 2 21
RESOLUTION RANGE HIGH
2.8
RESOLUTION RANGE LOW
50
PUBMED ID
DOI
10.1016/J.BMCL.2009.10.108

Chains

Structure ChainTarget ProteinGeneExpression SystemOrganismSynonymsActions
P36897 TGFBR1, TGFBRI SPODOPTERA FRUGIPERDA HUMAN TRANSFORMING GROWTH FACTOR-BETA RECEPTOR TYPE I,TGF-BETA RECEPTOR TYPE I, TGF-BETA TYPE I RECEPTOR, TBETAR-I, TGFR-1, SERINE/THREONINE-PROTEIN KINASE RECEPTOR R4,SKR4, ACTIVIN RECEPTOR-LIKE KINASE 5, ALK-5 HUMAN
TRANSFORMING GROWTH FACTOR-BETA RECEPTOR TYPE I,TG ...
Mutations
P36897 TGFBR1, TGFBRI SPODOPTERA FRUGIPERDA HUMAN TRANSFORMING GROWTH FACTOR-BETA RECEPTOR TYPE I,TGF-BETA RECEPTOR TYPE I, TGF-BETA TYPE I RECEPTOR, TBETAR-I, TGFR-1, SERINE/THREONINE-PROTEIN KINASE RECEPTOR R4,SKR4, ACTIVIN RECEPTOR-LIKE KINASE 5, ALK-5 HUMAN
TRANSFORMING GROWTH FACTOR-BETA RECEPTOR TYPE I,TG ...
Mutations
P36897 TGFBR1, TGFBRI SPODOPTERA FRUGIPERDA HUMAN TRANSFORMING GROWTH FACTOR-BETA RECEPTOR TYPE I,TGF-BETA RECEPTOR TYPE I, TGF-BETA TYPE I RECEPTOR, TBETAR-I, TGFR-1, SERINE/THREONINE-PROTEIN KINASE RECEPTOR R4,SKR4, ACTIVIN RECEPTOR-LIKE KINASE 5, ALK-5 HUMAN
TRANSFORMING GROWTH FACTOR-BETA RECEPTOR TYPE I,TG ...
Mutations
P36897 TGFBR1, TGFBRI SPODOPTERA FRUGIPERDA HUMAN TRANSFORMING GROWTH FACTOR-BETA RECEPTOR TYPE I,TGF-BETA RECEPTOR TYPE I, TGF-BETA TYPE I RECEPTOR, TBETAR-I, TGFR-1, SERINE/THREONINE-PROTEIN KINASE RECEPTOR R4,SKR4, ACTIVIN RECEPTOR-LIKE KINASE 5, ALK-5 HUMAN
TRANSFORMING GROWTH FACTOR-BETA RECEPTOR TYPE I,TG ...
Mutations
P36897 TGFBR1, TGFBRI SPODOPTERA FRUGIPERDA HUMAN TRANSFORMING GROWTH FACTOR-BETA RECEPTOR TYPE I,TGF-BETA RECEPTOR TYPE I, TGF-BETA TYPE I RECEPTOR, TBETAR-I, TGFR-1, SERINE/THREONINE-PROTEIN KINASE RECEPTOR R4,SKR4, ACTIVIN RECEPTOR-LIKE KINASE 5, ALK-5 HUMAN
TRANSFORMING GROWTH FACTOR-BETA RECEPTOR TYPE I,TG ...
Mutations
NGL Viewer is used for the molecular visualization.
  • AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
  • AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402