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3D Structure View

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GENERAL
TITLE
CFMS TYROSINE KINASE IN COMPLEX WITH 5-CYANO-FURAN-2-CARBOXYLIC ACID [4-(4-METHYL-PIPERAZIN-1-YL)-2-PIPERIDIN-1-YL-PHENYL]-AMIDE
DATE LAST MODIFIED
13 Oct 2021
RELEASE
1 Dec 2010
OBSOLETE
CLASSIFICATION
TRANSFERASE/TRANSFERASE INHIBITOR
EXPERIMENT TYPE
X-RAY DIFFRACTION
SPACE GROUP
H 3
RESOLUTION RANGE HIGH
2.4
RESOLUTION RANGE LOW
16.16
PUBMED ID
DOI
10.1021/JM200900Q

Chains

Structure ChainTarget ProteinGeneExpression SystemOrganismSynonymsActions
P07333 CSF1R, FGFR1 SPODOPTERA FRUGIPERDA HOMO SAPIENS C-FMS, FGFR-1RECEPTOR KINASE INSERT DOMAIN HOMO SAPIENS
C-FMS, FGFR-1RECEPTOR KINASE INSERT DOMAIN
Mutations
NGL Viewer is used for the molecular visualization.
  • AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
  • AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402