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GENERAL
TITLE
STRUCTURAL AND THERMODYNAMIC CHARACTERIZATION OF THE TYK2 AND JAK3 KINASE DOMAINS IN COMPLEX WITH CP-690550 AND CMP-6
DATE LAST MODIFIED
13 Oct 2021
RELEASE
2 Jun 2010
OBSOLETE
CLASSIFICATION
TRANSFERASE
EXPERIMENT TYPE
X-RAY DIFFRACTION
SPACE GROUP
P 21 21 21
RESOLUTION RANGE HIGH
1.74
RESOLUTION RANGE LOW
25.13
PUBMED ID
DOI
10.1016/J.JMB.2010.05.020
LIGANDS

Chains

Structure ChainTarget ProteinGeneExpression SystemOrganismSynonymsActions
P52333 JAK3 SPODOPTERA FRUGIPERDA HUMAN JANUS KINASE 3, JAK-3, LEUKOCYTE JANUS KINASE, L-JAK HUMAN
JANUS KINASE 3, JAK-3, LEUKOCYTE JANUS KINASE, L-J ...
Mutations
NGL Viewer is used for the molecular visualization.
  • AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
  • AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402