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GENERAL
TITLE
X-RAY CRYSTAL STRUCTURE OF ITK COMPLEXED WITH INHIBITOR RO5191614
DATE LAST MODIFIED
18 Aug 2010
RELEASE
30 Jun 2010
OBSOLETE
CLASSIFICATION
TRANSFERASE
EXPERIMENT TYPE
X-RAY DIFFRACTION
SPACE GROUP
C 1 2 1
RESOLUTION RANGE HIGH
1.72
RESOLUTION RANGE LOW
40
PUBMED ID
DOI
10.1111/J.1747-0285.2010.00993.X
LIGANDS

Chains

Structure ChainTarget ProteinGeneExpression SystemOrganismSynonymsActions
Q08881 ITK, EMT, LYK SPODOPTERA FRUGIPERDA HUMAN T-CELL-SPECIFIC KINASE, TYROSINE-PROTEIN KINASE LYK, KINASEEMT HUMAN
T-CELL-SPECIFIC KINASE, TYROSINE-PROTEIN KINASE LY ...
Mutations
NGL Viewer is used for the molecular visualization.
  • AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
  • AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402