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GENERAL
TITLE
THE MCL-1 BH3 HELIX IS AN EXCLUSIVE MCL-1 INHIBITOR AND APOPTOSIS SENSITIZER
DATE LAST MODIFIED
6 Oct 2021
RELEASE
23 Jun 2010
OBSOLETE
CLASSIFICATION
APOPTOSIS/APOPTOSIS REGULATOR
EXPERIMENT TYPE
X-RAY DIFFRACTION
SPACE GROUP
P 21 21 21
RESOLUTION RANGE HIGH
2.32
RESOLUTION RANGE LOW
50
PUBMED ID
DOI
10.1038/NCHEMBIO.391
LIGANDS

Chains

Structure ChainTarget ProteinGeneExpression SystemOrganismSynonimsActions
P02866 BCL2L3, MCL-1, MCL1 ESCHERICHIA COLI HUMAN
BCL-2-RELATED PROTEIN EAT/MCL1, MCL1/EAT, BCL-2-LI ...
Q8NXI6 -- -- --
BCL-2-RELATED PROTEIN EAT/MCL1, MCL1/EAT, BCL-2-LI ...
NGL Viewer is used for the molecular visualization.
  • AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
  • AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402