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GENERAL
TITLE
CRYSTAL STRUCTURE OF THE ACVRL1 (ALK1) KINASE DOMAIN BOUND TO LDN- 193189
DATE LAST MODIFIED
1 Apr 2015
RELEASE
21 Jul 2010
OBSOLETE
CLASSIFICATION
TRANSFERASE
EXPERIMENT TYPE
X-RAY DIFFRACTION
SPACE GROUP
P 32
RESOLUTION RANGE HIGH
2.65
RESOLUTION RANGE LOW
58.99
PUBMED ID
DOI
10.1007/S10456-014-9457-Y
LIGANDS

Chains

Structure ChainTarget ProteinGeneExpression SystemOrganismSynonymsActions
P37023 ACVRL1, ACVRL1 (ALK1), ACVRLK1, ALK1 SPODOPTERA FRUGIPERDA HUMAN SKR3, ACTIVIN RECEPTOR-LIKE KINASE 1, ALK-1, TGF-BSUPERFAMILY RECEPTOR TYPE I, TSR-I HUMAN
SKR3, ACTIVIN RECEPTOR-LIKE KINASE 1, ALK-1, TGF-B ...
Mutations
P37023 ACVRL1, ACVRL1 (ALK1), ACVRLK1, ALK1 SPODOPTERA FRUGIPERDA HUMAN SKR3, ACTIVIN RECEPTOR-LIKE KINASE 1, ALK-1, TGF-BSUPERFAMILY RECEPTOR TYPE I, TSR-I HUMAN
SKR3, ACTIVIN RECEPTOR-LIKE KINASE 1, ALK-1, TGF-B ...
Mutations
P37023 ACVRL1, ACVRL1 (ALK1), ACVRLK1, ALK1 SPODOPTERA FRUGIPERDA HUMAN SKR3, ACTIVIN RECEPTOR-LIKE KINASE 1, ALK-1, TGF-BSUPERFAMILY RECEPTOR TYPE I, TSR-I HUMAN
SKR3, ACTIVIN RECEPTOR-LIKE KINASE 1, ALK-1, TGF-B ...
Mutations
P37023 ACVRL1, ACVRL1 (ALK1), ACVRLK1, ALK1 SPODOPTERA FRUGIPERDA HUMAN SKR3, ACTIVIN RECEPTOR-LIKE KINASE 1, ALK-1, TGF-BSUPERFAMILY RECEPTOR TYPE I, TSR-I HUMAN
SKR3, ACTIVIN RECEPTOR-LIKE KINASE 1, ALK-1, TGF-B ...
Mutations
P37023 ACVRL1, ACVRL1 (ALK1), ACVRLK1, ALK1 SPODOPTERA FRUGIPERDA HUMAN SKR3, ACTIVIN RECEPTOR-LIKE KINASE 1, ALK-1, TGF-BSUPERFAMILY RECEPTOR TYPE I, TSR-I HUMAN
SKR3, ACTIVIN RECEPTOR-LIKE KINASE 1, ALK-1, TGF-B ...
Mutations
P37023 ACVRL1, ACVRL1 (ALK1), ACVRLK1, ALK1 SPODOPTERA FRUGIPERDA HUMAN SKR3, ACTIVIN RECEPTOR-LIKE KINASE 1, ALK-1, TGF-BSUPERFAMILY RECEPTOR TYPE I, TSR-I HUMAN
SKR3, ACTIVIN RECEPTOR-LIKE KINASE 1, ALK-1, TGF-B ...
Mutations
P37023 ACVRL1, ACVRL1 (ALK1), ACVRLK1, ALK1 SPODOPTERA FRUGIPERDA HUMAN SKR3, ACTIVIN RECEPTOR-LIKE KINASE 1, ALK-1, TGF-BSUPERFAMILY RECEPTOR TYPE I, TSR-I HUMAN
SKR3, ACTIVIN RECEPTOR-LIKE KINASE 1, ALK-1, TGF-B ...
Mutations
P37023 ACVRL1, ACVRL1 (ALK1), ACVRLK1, ALK1 SPODOPTERA FRUGIPERDA HUMAN SKR3, ACTIVIN RECEPTOR-LIKE KINASE 1, ALK-1, TGF-BSUPERFAMILY RECEPTOR TYPE I, TSR-I HUMAN
SKR3, ACTIVIN RECEPTOR-LIKE KINASE 1, ALK-1, TGF-B ...
Mutations
P37023 ACVRL1, ACVRL1 (ALK1), ACVRLK1, ALK1 SPODOPTERA FRUGIPERDA HUMAN SKR3, ACTIVIN RECEPTOR-LIKE KINASE 1, ALK-1, TGF-BSUPERFAMILY RECEPTOR TYPE I, TSR-I HUMAN
SKR3, ACTIVIN RECEPTOR-LIKE KINASE 1, ALK-1, TGF-B ...
Mutations
P37023 ACVRL1, ACVRL1 (ALK1), ACVRLK1, ALK1 SPODOPTERA FRUGIPERDA HUMAN SKR3, ACTIVIN RECEPTOR-LIKE KINASE 1, ALK-1, TGF-BSUPERFAMILY RECEPTOR TYPE I, TSR-I HUMAN
SKR3, ACTIVIN RECEPTOR-LIKE KINASE 1, ALK-1, TGF-B ...
Mutations
NGL Viewer is used for the molecular visualization.
  • AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
  • AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402