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GENERAL
TITLE
CRYSTAL STRUCTURE OF HUMAN CYTOCHROME P4503A4 BOUND TO AN INHIBITOR RITONAVIR
DATE LAST MODIFIED
8 Nov 2017
RELEASE
20 Oct 2010
OBSOLETE
CLASSIFICATION
OXIDOREDUCTASE/OXIDOREDUCTASE INHIBITOR
EXPERIMENT TYPE
X-RAY DIFFRACTION
SPACE GROUP
C 1 2 1
RESOLUTION RANGE HIGH
2
RESOLUTION RANGE LOW
77.38
PUBMED ID
DOI
10.1073/PNAS.1010693107

Chains

Structure ChainTarget ProteinGeneExpression SystemOrganismSynonymsActions
P08684 CYP3A3, CYP3A4 ESCHERICHIA COLI HUMAN QUININE 3-MONOOXYGENASE, CYPIIIA4, NIFEDIPINE OXIDASE,CYTOCHROME P450 3A3, CYPIIIA3, CYTOCHROME P450 HLP,TAUROCHENODEOXYCHOLATE 6-ALPHA-HYDROXYLASE, CYTOCHROME P450 NF-25,CYTOCHROME P450-PCN1, ALBENDAZOLE MONOOXYGENASE, ALBENDAZOLESULFOXIDASE HUMAN
QUININE 3-MONOOXYGENASE, CYPIIIA4, NIFEDIPINE OXID ...
Mutations
P08684 CYP3A3, CYP3A4 ESCHERICHIA COLI HUMAN QUININE 3-MONOOXYGENASE, CYPIIIA4, NIFEDIPINE OXIDASE,CYTOCHROME P450 3A3, CYPIIIA3, CYTOCHROME P450 HLP,TAUROCHENODEOXYCHOLATE 6-ALPHA-HYDROXYLASE, CYTOCHROME P450 NF-25,CYTOCHROME P450-PCN1, ALBENDAZOLE MONOOXYGENASE, ALBENDAZOLESULFOXIDASE HUMAN
QUININE 3-MONOOXYGENASE, CYPIIIA4, NIFEDIPINE OXID ...
Mutations
NGL Viewer is used for the molecular visualization.
  • AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
  • AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402