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GENERAL
TITLE
CRYSTAL STRUCTURE OF THE ACVR1 KINASE DOMAIN IN COMPLEX WITH THE IMIDAZO[1,2-B]PYRIDAZINE INHIBITOR K00507
DATE LAST MODIFIED
8 Nov 2017
RELEASE
13 Oct 2010
OBSOLETE
CLASSIFICATION
TRANSFERASE/TRANSFERASE INHIBITOR
EXPERIMENT TYPE
X-RAY DIFFRACTION
SPACE GROUP
C 2 2 21
RESOLUTION RANGE HIGH
2
RESOLUTION RANGE LOW
69.48
PUBMED ID
-
DOI
--
PDBe
3OOM
Chains
| Structure Chain | Target Protein | Gene | Expression System | Organism | Synonyms | Actions | ||
|---|---|---|---|---|---|---|---|---|
| Q04771 | ACVR1, ACVRLK2 | SPODOPTERA FRUGIPERDA | HUMAN | ACTIVIN RECEPTOR TYPE I, ACTR-I, SERINE/THREONINE-PROTEINKINASE RECEPTOR R1, SKR1, ACTIVIN RECEPTOR-LIKE KINASE 2, ALK-2, TGF-B SUPERFAMILY RECEPTOR TYPE I, TSR-I | HUMAN | ACTIVIN RECEPTOR TYPE I, ACTR-I, SERINE/THREONINE- ... | Mutations |
NGL Viewer is used for the molecular visualization.
- AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
- AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402