3OW4 logo

3OW4

3D Structure View

Loading...

More Info

GENERAL
TITLE
DISCOVERY OF DIHYDROTHIENO- AND DIHYDROFUROPYRIMIDINES AS POTENT PAN AKT INHIBITORS
DATE LAST MODIFIED
24 Nov 2010
RELEASE
10 Nov 2010
OBSOLETE
CLASSIFICATION
TRANSFERASE/TRANSFERASE INHIBITOR
EXPERIMENT TYPE
X-RAY DIFFRACTION
SPACE GROUP
P 1 21 1
RESOLUTION RANGE HIGH
2.6
RESOLUTION RANGE LOW
30
PUBMED ID
DOI
10.1016/J.BMCL.2010.09.112
PDBe
--

Chains

Structure ChainTarget ProteinGeneExpression SystemOrganismSynonymsActions
P31749 AKT1, PKB, RAC SPODOPTERA FRUGIPERDA HUMAN RAC-PK-ALPHA, PROTEIN KINASE B, PKB, PROTO-ONCOGENE C-AKT HUMAN
RAC-PK-ALPHA, PROTEIN KINASE B, PKB, PROTO-ONCOGEN ...
Mutations
P31749 AKT1, PKB, RAC SPODOPTERA FRUGIPERDA HUMAN RAC-PK-ALPHA, PROTEIN KINASE B, PKB, PROTO-ONCOGENE C-AKT HUMAN
RAC-PK-ALPHA, PROTEIN KINASE B, PKB, PROTO-ONCOGEN ...
Mutations
P49841 -- -- -- -- -- -- Mutations
P49841 -- -- -- -- -- -- Mutations
NGL Viewer is used for the molecular visualization.
  • AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
  • AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402