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GENERAL
TITLE
HIGHLY SELECTIVE C-JUN N-TERMINAL KINASE (JNK) 2 AND 3 INHIBITORS WITH IN VITRO CNS-LIKE PHARMACOKINETIC PROPERTIES
DATE LAST MODIFIED
-
RELEASE
17 Aug 2011
OBSOLETE
CLASSIFICATION
TRANSHERASE/TRANSFERASE INHIBITOR
EXPERIMENT TYPE
X-RAY DIFFRACTION
SPACE GROUP
P 21 21 21
RESOLUTION RANGE HIGH
1.7
RESOLUTION RANGE LOW
59.44
PUBMED ID
DOI
10.1016/J.BMCL.2010.11.010
PDBe
--
LIGANDS
Chains
| Structure Chain | Target Protein | Gene | Expression System | Organism | Synonyms | Actions | ||
|---|---|---|---|---|---|---|---|---|
| P53779 | MAPK10, JNK3, JNK3A, PRKM10 | ESCHERICHIA COLI | HUMAN | MAP KINASE 10, MAPK 10, STRESS-ACTIVATED PROTEIN KINASEJNK3, C-JUN N-TERMINAL KINASE 3, MAP KINASE P49 3F12 | HUMAN | MAP KINASE 10, MAPK 10, STRESS-ACTIVATED PROTEIN K ... | Mutations |
NGL Viewer is used for the molecular visualization.
- AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
- AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402