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GENERAL
TITLE
CRYSTAL STRUCTURE OF BTK KINASE DOMAIN COMPLEXED WITH 3-(2,6-DICHLORO- PHENYL)-7-[4-(2-DIETHYLAMINO-ETHOXY)-PHENYLAMINO]-1-METHYL-3,4- DIHYDRO-1H-PYRIMIDO[4,5-D]PYRIMIDIN-2-ONE
DATE LAST MODIFIED
27 Apr 2011
RELEASE
12 Jan 2011
OBSOLETE
CLASSIFICATION
TRANSFERASE/INHIBITOR
EXPERIMENT TYPE
X-RAY DIFFRACTION
SPACE GROUP
P 21 21 2
RESOLUTION RANGE HIGH
2
RESOLUTION RANGE LOW
40
PUBMED ID
DOI
10.1002/PRO.575
LIGANDS

Chains

Structure ChainTarget ProteinGeneExpression SystemOrganismSynonymsActions
Q06187 AGMX1, ATK, BPK, BTK SPODOPTERA FRUGIPERDA HUMAN AGAMMAGLOBULINAEMIA TYROSINE KINASE, ATK, B-CELL PROGENITORKINASE, BPK, BRUTON TYROSINE KINASE HUMAN
AGAMMAGLOBULINAEMIA TYROSINE KINASE, ATK, B-CELL P ...
Mutations
NGL Viewer is used for the molecular visualization.
  • AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
  • AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402