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GENERAL
TITLE
CRYSTAL STRUCTURE OF JAK3 COMPLEXED WITH A POTENT ATP SITE INHIBITOR SHOWING HIGH SELECTIVITY WITHIN THE JANUS KINASE FAMILY
DATE LAST MODIFIED
28 Sept 2011
RELEASE
29 Dec 2010
OBSOLETE
CLASSIFICATION
TRANSFERASE/TRANSFERASE INHIBITOR
EXPERIMENT TYPE
X-RAY DIFFRACTION
SPACE GROUP
P 21 21 21
RESOLUTION RANGE HIGH
2.2
RESOLUTION RANGE LOW
59.87
PUBMED ID
DOI
10.1021/JM101157Q
LIGANDS

Chains

Structure ChainTarget ProteinGeneExpression SystemOrganismSynonymsActions
P52333 JAK3 SPODOPTERA FRUGIPERDA HUMAN JANUS KINASE 3, JAK-3, LEUKOCYTE JANUS KINASE, L-JAK HUMAN
JANUS KINASE 3, JAK-3, LEUKOCYTE JANUS KINASE, L-J ...
Mutations
NGL Viewer is used for the molecular visualization.
  • AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
  • AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402