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GENERAL
TITLE
HER2 KINASE DOMAIN COMPLEXED WITH TAK-285
DATE LAST MODIFIED
14 Dec 2011
RELEASE
23 Nov 2011
OBSOLETE
CLASSIFICATION
TRANSFERASE/TRANSFERASE INHIBITOR
EXPERIMENT TYPE
X-RAY DIFFRACTION
SPACE GROUP
P 1
RESOLUTION RANGE HIGH
3.2
RESOLUTION RANGE LOW
50
PUBMED ID
DOI
10.1021/JM2008634
LIGANDS

Chains

Structure ChainTarget ProteinGeneExpression SystemOrganismSynonymsActions
P04626 ERBB2, HER2, MLN19, NEU, NGL SPODOPTERA FRUGIPERDA HUMAN METASTATIC LYMPH NODE GENE 19 PROTEIN, MLN 19, PROTO-ONCOGENE NEU, PROTO-ONCOGENE C-ERBB-2, TYROSINE KINASE-TYPE CELLSURFACE RECEPTOR HER2, P185ERBB2 HUMAN
METASTATIC LYMPH NODE GENE 19 PROTEIN, MLN 19, PRO ...
Mutations
P04626 ERBB2, HER2, MLN19, NEU, NGL SPODOPTERA FRUGIPERDA HUMAN METASTATIC LYMPH NODE GENE 19 PROTEIN, MLN 19, PROTO-ONCOGENE NEU, PROTO-ONCOGENE C-ERBB-2, TYROSINE KINASE-TYPE CELLSURFACE RECEPTOR HER2, P185ERBB2 HUMAN
METASTATIC LYMPH NODE GENE 19 PROTEIN, MLN 19, PRO ...
Mutations
P04626 ERBB2, HER2, MLN19, NEU, NGL SPODOPTERA FRUGIPERDA HUMAN METASTATIC LYMPH NODE GENE 19 PROTEIN, MLN 19, PROTO-ONCOGENE NEU, PROTO-ONCOGENE C-ERBB-2, TYROSINE KINASE-TYPE CELLSURFACE RECEPTOR HER2, P185ERBB2 HUMAN
METASTATIC LYMPH NODE GENE 19 PROTEIN, MLN 19, PRO ...
Mutations
P04626 ERBB2, HER2, MLN19, NEU, NGL SPODOPTERA FRUGIPERDA HUMAN METASTATIC LYMPH NODE GENE 19 PROTEIN, MLN 19, PROTO-ONCOGENE NEU, PROTO-ONCOGENE C-ERBB-2, TYROSINE KINASE-TYPE CELLSURFACE RECEPTOR HER2, P185ERBB2 HUMAN
METASTATIC LYMPH NODE GENE 19 PROTEIN, MLN 19, PRO ...
Mutations
NGL Viewer is used for the molecular visualization.
  • AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
  • AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402