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GENERAL
TITLE
HER2 KINASE DOMAIN COMPLEXED WITH TAK-285
DATE LAST MODIFIED
14 Dec 2011
RELEASE
23 Nov 2011
OBSOLETE
CLASSIFICATION
TRANSFERASE/TRANSFERASE INHIBITOR
EXPERIMENT TYPE
X-RAY DIFFRACTION
SPACE GROUP
P 1
RESOLUTION RANGE HIGH
3.2
RESOLUTION RANGE LOW
50
PUBMED ID
DOI
10.1021/JM2008634
PDBe
3RCD
LIGANDS
Chains
| Structure Chain | Target Protein | Gene | Expression System | Organism | Synonyms | Actions | ||
|---|---|---|---|---|---|---|---|---|
| P04626 | ERBB2, HER2, MLN19, NEU, NGL | SPODOPTERA FRUGIPERDA | HUMAN | METASTATIC LYMPH NODE GENE 19 PROTEIN, MLN 19, PROTO-ONCOGENE NEU, PROTO-ONCOGENE C-ERBB-2, TYROSINE KINASE-TYPE CELLSURFACE RECEPTOR HER2, P185ERBB2 | HUMAN | METASTATIC LYMPH NODE GENE 19 PROTEIN, MLN 19, PRO ... | Mutations | |
| P04626 | ERBB2, HER2, MLN19, NEU, NGL | SPODOPTERA FRUGIPERDA | HUMAN | METASTATIC LYMPH NODE GENE 19 PROTEIN, MLN 19, PROTO-ONCOGENE NEU, PROTO-ONCOGENE C-ERBB-2, TYROSINE KINASE-TYPE CELLSURFACE RECEPTOR HER2, P185ERBB2 | HUMAN | METASTATIC LYMPH NODE GENE 19 PROTEIN, MLN 19, PRO ... | Mutations | |
| P04626 | ERBB2, HER2, MLN19, NEU, NGL | SPODOPTERA FRUGIPERDA | HUMAN | METASTATIC LYMPH NODE GENE 19 PROTEIN, MLN 19, PROTO-ONCOGENE NEU, PROTO-ONCOGENE C-ERBB-2, TYROSINE KINASE-TYPE CELLSURFACE RECEPTOR HER2, P185ERBB2 | HUMAN | METASTATIC LYMPH NODE GENE 19 PROTEIN, MLN 19, PRO ... | Mutations | |
| P04626 | ERBB2, HER2, MLN19, NEU, NGL | SPODOPTERA FRUGIPERDA | HUMAN | METASTATIC LYMPH NODE GENE 19 PROTEIN, MLN 19, PROTO-ONCOGENE NEU, PROTO-ONCOGENE C-ERBB-2, TYROSINE KINASE-TYPE CELLSURFACE RECEPTOR HER2, P185ERBB2 | HUMAN | METASTATIC LYMPH NODE GENE 19 PROTEIN, MLN 19, PRO ... | Mutations |
NGL Viewer is used for the molecular visualization.
- AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
- AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402