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GENERAL
TITLE
CRYSTAL STRUCTURE OF THE CATALYTIC DOMAIN OF C-MET KINASE IN COMPLEX WITH ARQ 197
DATE LAST MODIFIED
28 Sept 2011
RELEASE
27 Apr 2011
OBSOLETE
CLASSIFICATION
TRANSFERASE/TRANSFERASE INHIBITOR
EXPERIMENT TYPE
X-RAY DIFFRACTION
SPACE GROUP
P 1
RESOLUTION RANGE HIGH
1.94
RESOLUTION RANGE LOW
50
PUBMED ID
DOI
10.1074/JBC.M110.213801
LIGANDS

Chains

Structure ChainTarget ProteinGeneExpression SystemOrganismSynonymsActions
P08581 MET ESCHERICHIA COLI HUMAN HGF RECEPTOR, HGF/SF RECEPTOR, PROTO-ONCOGENE C-MET, SCATTERFACTOR RECEPTOR, SF RECEPTOR, TYROSINE-PROTEIN KINASE MET HUMAN
HGF RECEPTOR, HGF/SF RECEPTOR, PROTO-ONCOGENE C-ME ...
Mutations
P08581 MET ESCHERICHIA COLI HUMAN HGF RECEPTOR, HGF/SF RECEPTOR, PROTO-ONCOGENE C-MET, SCATTERFACTOR RECEPTOR, SF RECEPTOR, TYROSINE-PROTEIN KINASE MET HUMAN
HGF RECEPTOR, HGF/SF RECEPTOR, PROTO-ONCOGENE C-ME ...
Mutations
NGL Viewer is used for the molecular visualization.
  • AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
  • AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402