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GENERAL
TITLE
CRYSTALS STRUCTURE OF JAK2 WITH A 1-AMINO-5H-PYRIDO[4,3-B]INDOL-4- CARBOXAMIDE INHIBITOR
DATE LAST MODIFIED
8 Nov 2017
RELEASE
21 Mar 2012
OBSOLETE
CLASSIFICATION
TRANSFERASE/TRANSFERASE INHIBITOR
EXPERIMENT TYPE
X-RAY DIFFRACTION
SPACE GROUP
P 65
RESOLUTION RANGE HIGH
2.5
RESOLUTION RANGE LOW
50
PUBMED ID
DOI
10.1021/JM200909U

Chains

Structure ChainTarget ProteinGeneExpression SystemOrganismSynonymsActions
O60674 JAK2 SPODOPTERA FRUGIPERDA HUMAN JANUS KINASE 2, JAK-2 HUMAN
JANUS KINASE 2, JAK-2
Mutations
NGL Viewer is used for the molecular visualization.
  • AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
  • AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402