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GENERAL
TITLE
CRYSTAL STRUCTURE OF HUMAN PLACENTAL AROMATASE COMPLEXED WITH BREAST CANCER DRUG EXEMESTANE
DATE LAST MODIFIED
8 Nov 2017
RELEASE
6 Jun 2012
OBSOLETE
CLASSIFICATION
OXIDOREDUCTASE/OXIDOREDUCTASE INHIBITOR
EXPERIMENT TYPE
X-RAY DIFFRACTION
SPACE GROUP
P 32 2 1
RESOLUTION RANGE HIGH
3.21
RESOLUTION RANGE LOW
121.79
PUBMED ID
DOI
10.1021/JM300930N

Chains

Structure ChainTarget ProteinGeneExpression SystemOrganismSynonymsActions
P11511 CYP19A1, ARO1, CYAR, CYP19 ESCHERICHIA COLI HUMAN AROMATASE, CYPXIX, CYTOCHROME P-450AROM, ESTROGEN SYNTHASE HUMAN
AROMATASE, CYPXIX, CYTOCHROME P-450AROM, ESTROGEN ...
Mutations
NGL Viewer is used for the molecular visualization.
  • AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
  • AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402