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GENERAL
TITLE
NOVEL ATP-COMPETITIVE MK2 INHIBITORS WITH POTENT BIOCHEMICAL AND CELL- BASED ACTIVITY THROUGHOUT THE SERIES
DATE LAST MODIFIED
11 Jan 2012
RELEASE
14 Dec 2011
OBSOLETE
CLASSIFICATION
TRANSFERASE/TRANSFERASE INHIBITOR
EXPERIMENT TYPE
X-RAY DIFFRACTION
SPACE GROUP
C 1 2 1
RESOLUTION RANGE HIGH
2.25
RESOLUTION RANGE LOW
44.6
PUBMED ID
DOI
10.1016/J.BMCL.2011.10.071
LIGANDS

Chains

Structure ChainTarget ProteinGeneExpression SystemOrganismSynonymsActions
Q16644 MAPKAPK3 ESCHERICHIA COLI HUMAN MK3, MAPK-ACTIVATED PROTEIN KINASE 3, MAPKAP KINASE 3,MAPKAPK-3, CHROMOSOME 3P KINASE, 3PK HUMAN
MK3, MAPK-ACTIVATED PROTEIN KINASE 3, MAPKAP KINAS ...
Mutations
NGL Viewer is used for the molecular visualization.
  • AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
  • AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402