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GENERAL
TITLE
CRYSTAL STRUCTURE OF HUMAN MEK-1 KINASE IN COMPLEX WITH UCB1353770 AND AMPPNP
DATE LAST MODIFIED
-
RELEASE
29 Feb 2012
OBSOLETE
CLASSIFICATION
TRANSFERASE/TRANSFERASE INHIBITOR
EXPERIMENT TYPE
X-RAY DIFFRACTION
SPACE GROUP
P 1 21 1
RESOLUTION RANGE HIGH
2.3
RESOLUTION RANGE LOW
30.29
PUBMED ID
DOI
10.1016/J.JSB.2012.01.002

Chains

Structure ChainTarget ProteinGeneExpression SystemOrganismSynonymsActions
Q02750 HUMAN MEK-1 KINASE, MAP2K1, MEK1, PRKMK1 ESCHERICHIA COLI HUMAN MAP KINASE KINASE 1, MAPKK 1, MKK1, ERK ACTIVATOR KINASE 1,MAPK/ERK KINASE 1, MEK 1 HUMAN
MAP KINASE KINASE 1, MAPKK 1, MKK1, ERK ACTIVATOR ...
Mutations
Q02750 HUMAN MEK-1 KINASE, MAP2K1, MEK1, PRKMK1 ESCHERICHIA COLI HUMAN MAP KINASE KINASE 1, MAPKK 1, MKK1, ERK ACTIVATOR KINASE 1,MAPK/ERK KINASE 1, MEK 1 HUMAN
MAP KINASE KINASE 1, MAPKK 1, MKK1, ERK ACTIVATOR ...
Mutations
NGL Viewer is used for the molecular visualization.
  • AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
  • AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402