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GENERAL
TITLE
CRYSTAL STRUCTURE OF BTK MUTANT (F435T,K596R) COMPLEXED WITH IMIDAZO[1,5-A]QUINOXALINE
DATE LAST MODIFIED
26 Oct 2011
RELEASE
12 Oct 2011
OBSOLETE
CLASSIFICATION
TRANSFERASE/TRANSFERASE INHIBITOR
EXPERIMENT TYPE
X-RAY DIFFRACTION
SPACE GROUP
P 1 21 1
RESOLUTION RANGE HIGH
1.65
RESOLUTION RANGE LOW
34.675
PUBMED ID
DOI
10.1016/J.BMCL.2011.09.008
LIGANDS

Chains

Structure ChainTarget ProteinGeneExpression SystemOrganismSynonymsActions
Q08881 ITK, EMT, LYK -- HUMAN BTK, BRUTON'S TYROSINE KINASE, KINASE EMT, T-CELL-SPECIFICKINASE, TYROSINE-PROTEIN KINASE LYK HUMAN
BTK, BRUTON'S TYROSINE KINASE, KINASE EMT, T-CELL- ...
Mutations
NGL Viewer is used for the molecular visualization.
  • AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
  • AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402