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GENERAL
TITLE
CRYSTAL STRUCTURE OF HUMAN ERK2 COMPLEXED WITH A MAPK DOCKING PEPTIDE
DATE LAST MODIFIED
31 Oct 2012
RELEASE
15 Aug 2012
OBSOLETE
CLASSIFICATION
TRANSFERASE
EXPERIMENT TYPE
X-RAY DIFFRACTION
SPACE GROUP
P 21 21 21
RESOLUTION RANGE HIGH
2.4
RESOLUTION RANGE LOW
47.1
PUBMED ID
DOI
10.1126/SCISIGNAL.2003004
LIGANDS

Chains

Structure ChainTarget ProteinGeneExpression SystemOrganismSynonymsActions
P28482 MAPK1, ERK2, PRKM1, PRKM2 ESCHERICHIA COLI HUMAN MAP KINASE 1, MAPK 1, ERT1, EXTRACELLULAR SIGNAL-REGULATEDKINASE 2, ERK-2, MAP KINASE ISOFORM P42, P42-MAPK, MITOGEN-ACTIVATEDPROTEIN KINASE 2, MAP KINASE 2, MAPK 2 HUMAN
MAP KINASE 1, MAPK 1, ERT1, EXTRACELLULAR SIGNAL-R ...
Mutations
Q15418 -- -- HUMAN S6K-ALPHA-1, 90 KDA RIBOSOMAL PROTEIN S6 KINASE 1, P90-RSK1, P90RSK1, P90S6K, MAP KINASE-ACTIVATED PROTEIN KINASE 1A, MAPK-ACTIVATED PROTEIN KINASE 1A, MAPKAP KINASE 1A, MAPKAPK-1A, RIBOSOMALS6 KINASE 1, RSK-1 HUMAN
S6K-ALPHA-1, 90 KDA RIBOSOMAL PROTEIN S6 KINASE 1, ...
Mutations
NGL Viewer is used for the molecular visualization.
  • AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
  • AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402