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GENERAL
TITLE
CRYSTAL STRUCTURE OF JNK3 COMPLEXED WITH CC-930, AN ORALLY ACTIVE ANTI-FIBROTIC JNK INHIBITOR
DATE LAST MODIFIED
8 Nov 2017
RELEASE
1 Feb 2012
OBSOLETE
CLASSIFICATION
TRANSFERASE/TRANSFERASE INHIBITOR
EXPERIMENT TYPE
X-RAY DIFFRACTION
SPACE GROUP
P 21 21 21
RESOLUTION RANGE HIGH
2.2
RESOLUTION RANGE LOW
50
PUBMED ID
DOI
10.1016/J.BMCL.2011.12.027
PDBe
3TTI
Chains
| Structure Chain | Target Protein | Gene | Expression System | Organism | Synonyms | Actions | ||
|---|---|---|---|---|---|---|---|---|
| P53779 | JNK3, JNK3A, MAPK10, PRKM10 | ESCHERICHIA COLI | HUMAN | MAP KINASE 10, MAPK 10, MAP KINASE P49 3F12, STRESS-ACTIVATED PROTEIN KINASE JNK3, C-JUN N-TERMINAL KINASE 3 | HUMAN | MAP KINASE 10, MAPK 10, MAP KINASE P49 3F12, STRES ... | Mutations |
NGL Viewer is used for the molecular visualization.
- AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
- AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402