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GENERAL
TITLE
CRYSTAL STRUCTURE OF HUMAN MENIN IN COMPLEX WITH MLL1 AND LEDGF
DATE LAST MODIFIED
21 Jun 2017
RELEASE
15 Feb 2012
OBSOLETE
CLASSIFICATION
TRANSCRIPTION
EXPERIMENT TYPE
X-RAY DIFFRACTION
SPACE GROUP
P 61 2 2
RESOLUTION RANGE HIGH
3
RESOLUTION RANGE LOW
100
PUBMED ID
DOI
10.1038/NATURE10806

Chains

Structure ChainTarget ProteinGeneExpression SystemOrganismSynonymsActions
O00255 MEN1, SCG2 ESCHERICHIA COLI HUMAN -- HUMAN -- Mutations
O00255 MEN1, SCG2 ESCHERICHIA COLI HUMAN -- HUMAN -- Mutations
O75475 PSIP1, DFS70, LEDGF, PSIP2 ESCHERICHIA COLI HUMAN CLL-ASSOCIATED ANTIGEN KW-7,DENSE FINE SPECKLES 70 KDAPROTEIN,DFS 70,TRANSCRIPTIONAL COACTIVATOR P75/P52 HUMAN
CLL-ASSOCIATED ANTIGEN KW-7,DENSE FINE SPECKLES 70 ...
Mutations
O75475 PSIP1, DFS70, LEDGF, PSIP2 ESCHERICHIA COLI HUMAN CLL-ASSOCIATED ANTIGEN KW-7,DENSE FINE SPECKLES 70 KDAPROTEIN,DFS 70,TRANSCRIPTIONAL COACTIVATOR P75/P52 HUMAN
CLL-ASSOCIATED ANTIGEN KW-7,DENSE FINE SPECKLES 70 ...
Mutations
Q03164 KMT2A, ALL1, CXXC7, HRX, HTRX, MLL, MLL1, TRX1 ESCHERICHIA COLI HUMAN LYSINE N-METHYLTRANSFERASE 2A,ALL-1,CXXC-TYPE ZINC FINGERPROTEIN 7,MYELOID/LYMPHOID OR MIXED-LINEAGE LEUKEMIA,MYELOID/LYMPHOIDOR MIXED-LINEAGE LEUKEMIA PROTEIN 1,TRITHORAX-LIKE PROTEIN,ZINCFINGER PROTEIN HRX HUMAN
LYSINE N-METHYLTRANSFERASE 2A,ALL-1,CXXC-TYPE ZINC ...
Mutations
Q03164 KMT2A, ALL1, CXXC7, HRX, HTRX, MLL, MLL1, TRX1 ESCHERICHIA COLI HUMAN LYSINE N-METHYLTRANSFERASE 2A,ALL-1,CXXC-TYPE ZINC FINGERPROTEIN 7,MYELOID/LYMPHOID OR MIXED-LINEAGE LEUKEMIA,MYELOID/LYMPHOIDOR MIXED-LINEAGE LEUKEMIA PROTEIN 1,TRITHORAX-LIKE PROTEIN,ZINCFINGER PROTEIN HRX HUMAN
LYSINE N-METHYLTRANSFERASE 2A,ALL-1,CXXC-TYPE ZINC ...
Mutations
NGL Viewer is used for the molecular visualization.
  • AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
  • AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402